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In clinical practice, injuries to the nerves around the body are common and often lead to functional disability. Due to a lack of background knowledge on pathophysiology, nerve repair outcomes were hit or miss in the past. Since Sunderland first discussed microsurgery in 1945, nerve repairs have been much more likely to work. In the last few decades, advances in microsurgery, knowledge of nerve repair, and ongoing research in molecular biology have made peripheral nerve surgery more successful. Nerve Damage Classification Neuropraxia, axonotmesis, and neurotmesis are the three main types of nerve damage. Temporary loss of function without disruption of...

Maintaining healthy nerves requires the B-complex vitamins B1, B6, and B12. These vitamins are called "neurotropic" nutrients because they help repair nerves and relieve symptoms like tingling and numbness. In addition to helping keep nerves healthy, the B vitamins work together to help heal damaged nerves and keep the nervous system in good shape. Taking a B vitamin complex may be more effective than taking the vitamins separately because each B vitamin contributes to nerve function in its unique way. Find out who can benefit from taking a vitamin B complex, how the three neurotropic vitamins B1, B6, and B12...

Traumatic Peripheral Nerve Damage (PNI), surgical resection, iatrogenic injury, or toxicity from local anesthetics are all potential causes. Damage to peripheral nerves can cause weakness, numbness, paresthesia, pain, and changes in how the body works. Since PNI has been linked to inflammatory responses and nerve degeneration, stopping these could help patients feel better. Many different nutrients have been studied for their potential to mitigate PNI's unfavorable effects. The recovery rate after PNI in animal models is significantly increased by administering alpha-lipoic acid, cytidine diphosphate-choline (CDP Choline), curcumin, melatonin, vitamin B12, and vitamin E. There is a lot of evidence from...

Information from the body's extremities reaches the central nervous system via the peripheral nerves. Injury to these nerves affects their ability to send signals, leading to a wide range of painful or unpleasant feelings. Medical professionals refer to damage to the peripheral nerves as neuropathy or nerve damage. Peripheral neuropathy can cause various painful symptoms, including tingling, burning, and stabbing pains. As neuropathy commonly affects the hands and feet, the symptoms may begin in these areas. However, since the peripheral nerves are spread throughout the body, it is possible to experience symptoms in other areas, as well as experiencing different...